Innovative drug infusion technology for laboratory animals.

Summary of iPRECIO®      

The World's First Dual Inlet Ambulatory Infusion Pump

The iPRECIO® Dual is the world's first dual inlet ambulatory infusion pump. Dual reservoirs for 2 test articles or 1 test article and 1 physiological saline. It will use Orchesta®s pump transceiver module, for wireless programming, control and monitoring.

 

   Key Features       
  • Dual Inlet
  • IEEE 802.15.4 (compatible with Orchesta® software and wireless network) for programming, real-time dosing control and monitoring
  • 186 g for complete package (pump with battery and cassette)
  • All pump events are logged and time/date stamp
  • GLP and Part 11 compliant
This innovative designed iPRECIO® Dual will allow extremely sensitive safety pharmacology studies to be carried out remotely without any interaction with the animals from several hours pre- dose to 20/24 hours post-dose. It will no longer be necessary to enter the animal room to remove the pump and extract remaining test article from the animal’s internal catheter until the end of the physiological measurements. With IEEE 802.15.4 Orchesta® control, the pumps may also be activated manually and thus ensuring that good physiological conditions are obtained before starting the Bolus Injection procedure remotely.

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   Software for use with iPRECIO® DUAL Pump       
The dual channel infusion pump would initially infuse physiological saline to ensure good patency of catheter and to keep vein open (KVO)/maintainance(MA). The second reservoir would contain the test article. With Orchesta® for Dual, all the dead volumes may be automatically flushed out and the animal's internal catheter primed with test article with the appropriate volume for injection. The bolus injection is then initiated at programmed start times and durations. Upon completion of the bolus injection, the infusion flow-rate may be reduced to the minimum infusion flow-rate to KVO/MA or to stop the pump completely.

While iPRECIO® Dual and the Orchesta® software are tailored to safety assessment applications, the solution is directly applicable for a large range of tethered and ambulatory applications in both large and small animal models.


Orchesta
 
 
 
 

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