Innovative drug infusion technology for laboratory animals.
iPRECIO Programmable Minipumps for continuous delivery lenalidomide (LLD) in chronic lymphocytic leukemia (CLL). Video, https://youtu.be/d8CHR7et5zs from Start to 7 minutes: Rodent Studies of PK, Safety and Tolerability of LLD in Healthy and SCID Mice by Dr Jamie Oliver Chief Medical Officer of Starton Therapeutics (https://startontx.com/). IMS/SMP-300 for mice or larger used. Photo of SMP-200 for rats of larger shown.
New review article on iPRECIO® - Linkedin Article – “Programmable pumps offer precise and translatable delivery of compounds to stress-free animals” https://www.linkedin.com/pulse/programmable-pumps-offer-precise-translatable-delivery-tsung-tan/?trackingId=i9CxNGMbQJye6JF6HVLJSw%3D%3D
US20200330445A1: Continuous delivery of lenalidomide and other immunomodulatory agents "After the tumor reached an average size of 100-150 mm, iPrecio pump was surgically implanted into each of the mice . Dosing began twenty - four hours post pump implantation. Each of Groups 3-6 was treated lenalidomide via continuous subcutaneous infusion at different hourly rate. The dosing lasted 14 days followed by one day off the treatment and lasted for another 14 days . The iPrecio pump was replaced after 14 days." For full reference: - Click -
IMS-200 version 13 Revision 532renew has been released An important Application Software update has been released. Please contact us for downloading and installation instructions. Please share with us UCD-200 Serial Number. It can be found on the back of the programming device which plugs into the USB port of your PC. The upgrade is free and compatible with windows 10. Contact us <click here>
First introduced in July 19 2019 for mice, we are pleased to share that the first peer reviewed publication (JASN) referencing/using our IMS/SMP-310R has been published. “To study the effects of inhibiting central sympathetic outflow, groups of 5/6Nx mice received continuous intracerebroventricular (i.c.v.) infusions of clonidine (5.76 mg/kg per day) or artificial cerebral spinal fluid from the first day after operation for 4 weeks, using Micro Infusion Pumps (iPrecio SMP/IMS-310R model). “ Excerpt from Cao et al. - Sympathetic Overactivity in CKD Disrupts Buffering of Neurotransmission by Endothelium-Derived Hyperpolarizing Factor and Enhances Vasoconstriction. Click <here>.
Page top
Copyright © 2020 Primetech Corporation All rights reserved.