US20200330445A1: Continuous delivery of lenalidomide and other immunomodulatory agents
"After the tumor reached an average size of 100-150 mm, iPrecio pump was surgically implanted into each of the mice . Dosing began twenty - four hours post pump implantation. Each of Groups 3-6 was treated lenalidomide via continuous subcutaneous infusion at different hourly rate. The dosing lasted 14 days followed by one day off the treatment and lasted for another 14 days . The iPrecio pump was replaced after 14 days." For full reference: - Click -

IMS-200 version 13 Revision 532renew has been released
An important Application Software update has been released. Please contact us for downloading and installation instructions. Please share with us UCD-200 Serial Number. It can be found on the back of the programming device which plugs into the USB port of your PC. The upgrade is free and compatible with windows 10. Contact us <click here>

First introduced in July 19 2019 for mice, we are pleased to share that the first peer reviewed publication (JASN) referencing/using our IMS/SMP-310R has been published. “To study the effects of inhibiting central sympathetic outflow, groups of 5/6Nx mice received continuous intracerebroventricular (i.c.v.) infusions of clonidine (5.76 mg/kg per day) or artificial cerebral spinal fluid from the first day after operation for 4 weeks, using Micro Infusion Pumps (iPrecio SMP/IMS-310R model). “ Excerpt from Cao et al. - Sympathetic Overactivity in CKD Disrupts Buffering of Neurotransmission by Endothelium-Derived Hyperpolarizing Factor and Enhances Vasoconstriction. Click <here>.

Our Programmable iPRECIO minipumps used to administer humanized doses of antifungal. Advance Article Alert (August 1 2020) Journal of Antimicrobial Chemotherapy. Intermittent micafungin for prophylaxis in a rat model of chronic Candida albicans gut colonization [first study to administer humanized doses of antifungal treatment to rats via implantable iPRECIO pumps]
https://academic.oup.com/jac/article-abstract/doi/10.1093/jac/dkaa243/5877001.

Excerpt from publication: Pumps were pre-programmed to allow repeated infusion cycles of micafungin to simulate the expected systemic exposure of a human dose of 300mg every 72h or 55mg every 24h (Tables S1 and S2, available as Supplementary data at JAC Online).

Curious to learn more? Contact Primetech and ask us about trying out our IMS-200 Application Software <click here>

101 discreet infusion flow-rates and programmable infusions protocols (simple and complex)? Start all pumps simultaneously after recovery. Program starts and stops. Wondering how you would program this? Contact Primetech and ask us to have access to iPRECIO IMS-310R Group Profile or infusion < click here >. iPRECIO minipumps are the only programmable refillable and implantable drug delivery devices on the market.