Innovative drug infusion technology for laboratory animals.
Sponsored 2024 3Rs Sharing Conference April 17, 2024 Genentech Campus, San Francisco, California An in-person discussion-focused 3Rs conference hosted by the 3Rs Collaborative and the New Jersey Association for Biomedical Research. Check out agenda https://3rc.org/3rs-sharing-conference/ Published: 30 January 2024 from Genentech, 1 DNA Way, South San Francisco, An, Le, Tom De Bruyn, Jodie Pang, Savita Ubhayakar, Laurent Salphati, Xing Zhang, Liling Liu et al. "Early Stage Preclinical Formulation Strategies to Alter the Pharmacokinetic Profile of Two Small Molecule Therapeutics." Pharmaceuticals 17, no. 2 (2024): 179. https://www.mdpi.com/1424-8247/17/2/179 Keywords: drug delivery; PO; IV infusion; IP; SC; small molecule; PK profile; exposure
Download and install our Latest Application Software for IMS/SMP-310R which was released in January 2024. Includes Release Notes. Go to our support page https://www.iprecio.com/support/tabid/262/Default.aspx
6 new publications including 2 with STAR*METHODS (https://www.cell.com/cell/fulltext/S0092-8674(16)31072-8). These two publications mention administrating clinically relevant doses. Rodrigues, Marinelle, et al. "Susceptible bacteria “can” survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance." Cell Host & Microbe (2024). https://www.sciencedirect.com/science/article/abs/pii/S1931312824000167 Keywords: antibiotic resistance; antibiotic persistence; antibiotic tolerance; mammalian GI tract; bacterial survival; Escherichia coli; bacterial virulance Giri, Tusar, et al. "Oxytocin Induced Birth Causes Sex Specific Behavioral and Brain Connectivity Changes in Developing Rat Offspring." Iscience (2024). https://www.sciencedirect.com/science/article/pii/S2589004224001810 [Open Access] Subject areas: Endocrinology; Neuroscience; Behavioral neuroscience
7 new publications including Circadian and Pulsatile delivery. See https://www.iprecio.com/support/tabid/196/Default.aspx and https://www.iprecio.com/support/tabid/161/Default.aspx for full details. Here are 3:-
Tochinai, Ryota, et al. Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat. [Open Access] Experimental Animals (2023): 23-0087. https://www.jstage.jst.go.jp/article/expanim/advpub/0/advpub_23-0087/_article/-char/ja/ Key words: dystrophin deficiency, echocardiography, HCN channel, heart, tachycardia
Joshi, Pooja, et al. Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function and prevents sudden arrhythmic death in failing hearts. [Open Access] eLife 12 (2023) https://elifesciences.org/reviewed-preprints/88638v2 Keywords: Sudden cardiac death (SCD), heart failure (HF), ventricular tachycardia/fibrillation (VT/VF)
Bering, Tenna, et al., Circadian Clock Genes Are Regulated by Rhythmic Corticosterone at Physiological Levels in the Rat Hippocampus. Neuroendocrinology 113.10 (2023): 1076-1090. https://karger.com/nen/article/113/10/1076/860659 Keywords: Clock gene, Corticosterone, Hippocampus, Programmable pumps, Suprachiasmatic nucleus
[Webinar] DATE: Wednesday, September 20, 2023 iPRECIO Micro Infusion Pump by Primetech Corporation sponsors Test Method Webinar. Learn about the webinar New Horizons: Gonadotropin-Releasing Hormone and Cognition by the joining Vincent Prevot, PhD as he dives into the development and establishment of the gonadotropin-releasing hormone (GnRH) system and the importance of its first postnatal activation. The webinar series Neurophysiology: Exploring Basic Research & Clinical Consequences is with the American Physiological Society, Society for Neuroscience, Federation of European Neuroscience Societies - FENS, and the American Autonomic Society! Webinar and related Scientific Publications details have been updated in our iPRECIO Application Booklet on page 23. Contact iPRECIO Micro Infusion Pumps by Primetech Corporation.
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